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Wednesday, 18 June 2025

What saline can I use for injections?

Some people buy products, such as vitamin B12 in a powder form, which require to be dissolved in a liquid so they can be injected.

Hence the question as to what liquid that should be! 

  • It must be sterile. 
  • It must be saline (sodium chloride in water).
  • It should be an isotonic 0.9% saline solution.
  • It should be a non-pyrogenic saline for injection which is clearly identified as such.

Non-pyrogenic means: Non-fever inducing!

If you boiled water in a kettle, that water might well be sterile.

But the remains of any bacteria, fungal spores, etc., which will usually be present in the water, albeit in tiny amounts, can cause issues when injected. Even if the water was entirely safe for drinking before being boiled.

There are many sterile saline sources which are not non-pyrogenic and would be unsuitable for injection purposes. These include saline for nebulisers, for eye drops, or containing a preservative, or a lower concentration saline used for some infusions

Any individual product might or might not be OK but, unless officially non-pyrogenic, you simply cannot know it will be safe.

In other words, always get Saline for Injection that is appropriately labelled. In the UK, it would probably say:

Sodium Chloride 0.9% w/v Solution for Injection

In German, it would probably say: Injektionslösung

Though it might also have other wording like company and brand names, etc. 

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What saline can I use for injections?

Some people buy products, such as vitamin B12 in a powder form, which require to be dissolved in a liquid so they can be injected. Hence the...