Discussion
A widely discussed issue is whether Vitamin C enhances absorption of levothyroxine. For example, these two papers:
The interplay between vitamin C and thyroid.
https://europepmc.org/article/MED/37246589
https://doi.org/10.1002/edm2.432
Levothyroxine treatment and gastric juice pH in humans: the proof of concept.
https://europepmc.org/article/MED/35477833
https://doi.org/10.1007/s12020-022-03056-1
If you decide to try this approach, there are some important points.
Form of Vitamin C
There are several forms of Vitamin C. But the forms which are not ascorbic acid will not help.
That is, sodium ascorbate and calcium ascorbate are unlikely to have any positive effect.
Other Ingredients
And many forms of Vitamin C are not just the active ingredient but other substances like those in the list below. Some are very pure ascorbic acid but some have numerous other ingredients. And each of those ingredients needs to be considered.
- microcrystalline cellulose
- magnesium stearate
- polyethylene glycol
- sodium starch glycolate
- silica colloidal anhydrous
- talc
- syrup (sucrose)
- potato starch
- hypromellose (derived from cellulose) capsule
- calcium laurate
https://helvella.blogspot.com/2025/06/vitamin-c-and-levothyroxine.html
